DR. ALEXANDRE VIEIRA
Full Professor of Oral and Craniofacial Sciences, Pediatric Dentistry, Human Genetics and Anthropology
"The Overlooked Individual:Susceptibility to Dental Caries, Erosive Tooth Wear and MIH"
Human genetics is the discipline that deals with inheritance as it occurs in human beings. It has components of classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling, and to the list we can now add epigenetics. The main purpose of this presentation is to document the content specific of Cariology of 15 years of developing independent research on dental caries, erosive tooth wear, and MIH.
Dr. Vieira grew up in a low midclass family in Rio de Janeiro and it was his fate to have toothache. Treating those proved to continue to be memorable since the dentist suggested there was no need for the use of local anesthetics. This experience and later his need for orthodontic treatment, which was done at low cost at a local residency program at the Brazilian Dental Association, woke him to his interest in dentistry.
Dr. Vieira earned a DDS years later, graduating from the Federal University of Rio de Janeiro in January 17, 1992. After his mandatory military service as a dentist in the Brazilian Navy, he saved enough money to return to his studies and was admitted to a residency program at the same Brazilian Dental Association building he was once a patient in orthodontics in Dentistry for Individuals with Special Needs, which he finished in December of 1993. Since many cases were children, he decided to study pediatric dentistry and was admitted to the residency program in Pediatric Dentistry at his alma later Federal University of Rio de Janeiro, which he concluded in December 1994. That was followed by a Master’s program in Pediatric Dentistry in the same department and he defended his thesis June 20, 1997, working on fluoride release of glass ionomer composite hybrid materials. His interest in Cariology just grew from that first experience, as he went to earn a PhD in Genetics, working on genetics of cleft lip and palate, also at the Federal University of Rio de Janeiro. This experience brought the opportunity of a post-doc at the University of Iowa, focusing on human molecular genetics. He obtained his first NIH grant at the age of 33, and the idea was to look at dental developmental problems to analyze gene contributions to children born with cleft lip and palate. This protocol was developed in the Philippines on almost 75 families and 650 individuals and to define tooth agenesis, he devised a careful scoring of caries experience. With these data, he performed the first genome wide linkage study on dental caries and brought to light an emphasis that was lacking in the Cariology which is the focus on the susceptible individual. His group became one of the most visible one in the world with this approach of looking at genetic variation to suggest an explanation to individual susceptibility to oral disease. He has extended his studies to a number of topics in Cariology, including erosive tooth wear, molar incisor hypomineralization, and dental fluorosis. Particularly for dental caries, he has look at defining the disease beyond just the presence of absence of caries lesions, and has worked to unveil disease patterns and trajectories of lifetime disease of individuals to enhance his ability to identify biological etiological factors for dental caries. His studies currently combine genetic variation, microbiome and proteomics along with careful clinical descriptions.
To support these studies, he has created the Dental Registry and DNA Repository project, the only one in the world that keeps comprehensive dental clinical descriptions linked to a biological sample (saliva). Currently, the project has more than 6,700 participants.
Dr. Vieira has published more than 400 peer-reviewed papers, editorials, letter to the editor, book chapters. and books, including the Genetic Basis of Oral Health Conditions published by Springer, which was inspired by his worldwide recognized Craniofacial Genetics course that he teaches for 14 years in Pittsburgh. Also, among his publications, a paper that is the most cited per year on the cleft lip and palate field, and one on genetics of caries that was the most cited of the year of 2015 in Caries Research, elevating the impact factor of the journal at that time to almost 2.
He has mentored more than 200 students in his lab, from high school to post-docs, and has received a number of awards, including the Distinguished Scientist in Dental Caries Research Award from IADR in 2015, the Gies Award for best paper published at the Journal of Dental Research three times in 11 years (the only one on the history of the award), the Willian Gies Award of Vision from the ADEA Foundation in 2019, he was given chair # 87 on the Brazilian Academy of Dentistry in 2019, and received the ORCA Award in 2021. In 2020, he was elected to be president of the American Association for Dental Research (AADOCR).
He has lectured in all continents and has reviewed grants for agencies of several countries. He currently is Full Professor of Oral Biology, Pediatric Dentistry, Human Genetics, and Anthropology at the University of Pittsburgh School of Dental Medicine, and also serves as Director of Student Research and Director of Clinical Research in the school.
DR. DT. ALP ABİDİN ATEŞÇİ
"Digital anaesthesia in paediatric dentistry: Catching up with the new age"
Pain management in pediatric dentistry has always been an important element of a successful treatment. In recent years with the development of new technologies, the use of digital anesthesia systems has become quite widespread, especially in European countries. With digital anesthesia systems, it became possible to inject anesthetic solution in a constant speed, allowing patients to feel very little or no pain. In addition, thanks to the use of intraosseous anesthesia technique, clinicians can now inject the anesthetic solution to only one point, providing an effective and comfortable anesthesia. This presentation will convey to you in detail the effects of digital anesthesia systems on patient cooperation and comfort of the treatment with scientific data and clinical applications in pediatric dentistry.
Dr. Alp Abidin Ateşçi has qualified from Başkent University Faculty of Dentistry in 2014. Dr. Ateşçi has gained his PhD from the Department of Pedodontics at Ege University Health Sciences Institute in 2019. Since then, he has been practicing at private clinics and has been running his own practice since 2021. His areas of interest are regenerative endodontic treatments, vital pulp therapies, dental traumatology and pediatric zirconium crowns. He has published several articles in national and international indexed journals and has been a reviewer for the national journals. He is an active member of the Turkish Society of Paediatric Dentistry.
PROF. DR. MED. DENT. HABIL. CHRISTIAN H. SPLIETH
Professor & Head of Preventive and Paediatric Dentistry at the University of Greifswald/Germany
"Pediatric Dentistry: Back to the Future"
Pediatric dentistry is an established field which covers almost all aspects of dentistry in children. This is mainly determined by the epidemiologic basis where a great success story was achieved. In spite of a caries decline, mostly in the permanent dentition, the primary dentition exhibit high treatment need. Unfortunately, a polarization in a low number of children, often without sufficient coping skills is seen.
Apart from this, diagnostics and early treatment of malocclusion and malfunction, hard tissue disorders such as MIH and dental trauma will possibly be the most demanding tasks for future pediatric dentists.
Thus, the presentation will highlight:
- Prevention of early childhood caries
- Management of caries in primary teeth
- New techniques without „caries removal“
- Increasing cooperation via nitrous oxide sedation
- MIH, the new epidemia?
- Trauma: biological and forensic thinking
Dental Education: at School of Dentistry, University of Göttingen/Germany, Leeds/GB and Minnesota/USA
2000: PhD/Habilitation on „Caries prevalence, risk assessment and risk-specific prevention in children”
Specialist in Pediatric Dentistry by German Society for Pediatric Dentistry
Since 2000: Head of Community Dental Services Greifswald
April 2004: Head for Paediatric Dentistry and Prevention at the University Kiel/Germany
Since Dec. 2004: Head of Dept. for Preventive and Paediatric Dentistry at the University Greifswald/Germany (www.dental.uni-greifswald.de/abteilung/kinder/)
2013-2015: President of German Association for Pediatric Dentistry
2014: Co-President for European Organisation for Caries Research
2019-21: President ORCA (European Organisation for Caries Research)
Areas of interest: Paediatric Dentistry, Cariology, Epidemiology, Prevention, Community Dentistry, Health Economics
PROF. DR. MARCIO VIVAN CARDOSO
"Modern materials and techniques in adhesive restorative dentistry"
Promoting better quality of life is the new paradigm in healthcare and it cannot be otherwise in dentistry. Caries management has evolved from drilling and filling to a more holistic approach that includes the preservation of the tooth structure. This can be achieved through the proper use of modern restorative techniques and materials. Each clinical situation, however, has to be carefully evaluated before the most appropriate treatment option is defined. While composites still represent the standard choice for aesthetic problems, the treatment of caries and the promotion of health care demands alternative restorative materials. In many clinical circumstances, modern bioactive and biomimetic restoratives will certainly be the material of choice thanks to their ability to intimately interact with dental hard tissues promoting heath care in its most holistic sense. On the other side, more resistant materials may be the most suitable option whenever the tooth needs to be protected against crack propagation and fractures. But in this sense, what would be the limit between direct and indirect restorations? To get the most of each restorative treatment, it is crucial that the dentist can differentiate among the various kinds of modern materials, their indications, and how to use them correctly. These aspects will be presented in this lecture, as well as the latest developments in restorative dentistry
Prof. Dr. Marcio Vivan Cardoso graduated as a dentist at Sao Paulo University, Brazil, in 1997. At the same institution, he obtained his Master (MSc) and Doctorate (PhD) degrees in 2003 and 2007 respectively, both in the area of Restorative Dentistry. Besides pursuing experience as a dentist in both public and private sectors, he has been intensively involved in the academic formation of students at Sao Paulo University and continuing education of dental surgeons as a lecturer at different institutions, always focusing the areas of dental materials, minimal intervention dentistry and aesthetic dentistry. After his PhD, Prof. Dr. Vivan Cardoso was appointed as Pos-Doctorate Researcher at KU Leuven, Belgium, where he conducted research on biomaterials, producing a considerable number of scientific articles published in different international peer-reviewed journals. He is also the author of book chapters on Dental Materials and collaborates as a reviewer for international peer-reviewed journals. He follows nowadays a tenure academic track at KU Leuven, Belgium, as Assistant Professor and Coordinator of Clinical Skills Training Center.
DOÇ. DR. MUSTAFA GÜNDOĞAR
"Clinical Information for Next Generation Endodontics"
A new era has begun in the root canal treatment procedures performed, especially in countries such as the USA and Canada, where technological advancements in endodontics are frequently occurring. Minimal shaping of the root canal is performed, the entire canal is cleaned with GentleWave or laser technology, and the root canal filling can be completed in a single session with maximum preservation of tooth tissue. You can learn these practices, which form the basis of the new generation endodontics, and apply them effectively at your own practcie, which will increase both patient comfort and upgrade endodontic treatment success. This presentation will present you all the steps of the new generation endodontic treatments in the light of updated scientific data.
After qualifying from Marmara University Faculty of Dentistry in 2005, Dr Mustafa Gündoğar completed his PhD in Dental Diseases and Treatment at Marmara University Health Sciences Institute. Following this, he started working at the Medipol University Faculty of Dentistry, Department of Endodontics. He received the title of Associate Professor in 2020 at the Department of Endodontics of the same university, where he is still working at. His areas of interest are the operating principles of the nickel titanium rotary instruments and the latest developments in root canal irrigation. He has many publications in national and international indexed journals and is a reviewer in national and international journals. He is an active member of the Turkish Dental Association (TDB), Turkish Endodontics Association (TED), American Association Endodontists (AAE), and European Society Endodontics (ESE).
"The importance of meta analysis"
The number of scientific investigations is increasing rapidly nowadays. Studying the same subject by different researchers naturally yields different results. Evaluating different results and reaching a single decision as a result is a very difficult process. Meta-analysis is used in presenting more comprehensive and reliable meta-analysis by gathering the results obtained from the information stack created by the literature under a single roof. The planning process of the Meta-Analysis study, obtaining the data, transferring it to the computer program and interpreting the results will be shared with you in this presentation.
He was born in Trabzon in 1981. He graduated from Ondokuz Mayıs University, Department of Statistics in 2004. He received his master's degree in statistics in 2005 and his PhD in 2008. Dr. Murat has been working as a lecturer in the Department of Industrial Engineering since 2013. He developed an Online Statistical Automation System (www.eistatistik.com) supported by KOSGEB R&D and Innovation Support Program. During the data analysis process, he collaborated in more than ten thousand academic studies (dissertations and articles) especially by Dental Faculties, Medical and Health Sciences Faculties. In addition, he is currently working on virtual reality and augmented reality applications in the field of health sciences.
"Preventive and Interceptive Approaches with Clear Aligners in Children"
Collaboration of Paediatric Dentistry and Orthodontics is of utmost importance in healthy transitioning of children from primary to permanent dentition. With routine pedodontic assessments, good oral health of patients in the mixed dentition can be maintained starting from an early age. Thus, acquired orthodontic disorders can be reduced and the chance of success in orthodontic treatment is greatly increased.
The use of clear aligners in orthodontic treatments is increasing with the development of digital technologies and software. In addition, the demands of the Z-generation patients, who follow all the technological developments in the world and expect the same from the dentist, also support this increase. The use of transparent aligners with correct diagnosis and treatment planning give promising results in the orthodontic treatment of children.
In this presentation; the use of clear aligners in preventive and interceptive orthodontic treatments of children with carying malocclusions will be explained with case reports.
Sinem Ceylanoğlu graduated from Marmara University Faculty of Den-tistry in 2002 with the first degree. In the same year, she started her doctorate education in Marmara University Faculty of Dentistry, De-partment of Orthodontics. In 2008, she presented her doctorate thesis titled “Evaluation of tongue pressure changes before, during and after Crib appliance therapy in growing patients” and received the title of Or-thodontist. Since this date, she continues her profession as an Ortho-dontist in Allianoi oral and dental health clinics.
Sinem Ceylanoğlu has focused her clinical studies on clear aligner treatments in recent years.
"Stem cell therapies in dentistry"
Mesenchymal stem cells are defined as a heterogeneous population of the postnatal period that can self-renew, have multipotent differentiation potential and have immunomodulatory capacity.
According to the definition of the International Stem Cell and Gene Therapy Association (ISCT), it is defined as a cell group that can adhere to plastic surfaces, showing CD73, CD90 and CD105 surface markings on their surface, not showing CD34, CD45, CD11b, CD19 and HLA-DR surface markings from haematopoietic surface markings and having three-way (osteogenic, chondrogenic and adipogenic) differentiation potential. In the last decade, preclinical and clinical studies have become important due to the complementary effect of MSC’s on tissue regeneration, providing tissue hemostasis, modulating the immune system in autoimmune diseases, allergic diseases and inflammatory diseases. MSCs can be obtained from adult and neonatal tissues. MSC’s can be obtained from many different tissues such as bone marrow, adipose tissue, skin, umbilical cord, placenta and dental tissues under laboratory conditions. The ability of MSC’s can be isolated from such different tissues and the embryonic origin of these tissues also cause these cells to show different potentials. In 2000, MSC was first isolated from dental pulp tissue. In the course of time, stem cells have been isolated from different dental sources such as primary teeth (exfoliated deciduous teeth-SHED), apical papillae, dental follicle, apical papilla and dental follicle. Also in-vitro and in-vivo studies have been carried out with different regeneration approaches.
Like other stem cell sources, dental MSC’s can also show self-renewal, multipotent differentiation, and immunomodulatory/anti-inflammatory properties. With this feature, dental MSC’s take their place effectively in regenerative medicine and tissue engineering.
He completed his Allergy-Immunology PhD from the Department of Child Health and Diseases at Marmara University, Faculty of Medicine.
He received the title of Associate Professor in 2009. Since 2014, he has been working as a Professor in the Department of Pediatric Allergy-Immunology at Marmara University Faculty of Medicine. His studies are on the immunological basis of autoimmune and allergic diseases, immunomodulation and immunotherapy mechanisms, stem cell and cellular therapies. He conducted studies on T cell response in patients with atopic dermatitis in Davos, Switzerland. He worked in the Swedish-Romania-Turkey partnership Marie Curie Project in Sweden-Gothenburg, which investigated the relationship between atopic diseases and hygiene, and continued some of his work in Sweden. In recent years, he has been working on stem cell applications and immunomodulatory effects of mesenchymal stem cells in the treatment of atopic diseases, Crohn's disease and autoimmune diseases. He is a member of the Stem Cell Working Group at the Turkish Academy of Sciences (TÜBA). He is the founding member and 3rd term president of the Stem Cell and Cellular Therapies Association. He still continues his studies at Marmara University Faculty of Medicine, Pediatric Allergy-Immunology Department.
Dr. UĞUR TOKAY
"Next generation MTA-based biomaterials: NeoPUTTY ve NeoSealer FLo"
- Information about “where, when and how to use new materials with bio-ceramic content”
- Performance of materials in current treatment approaches.
- Information about cost and clinical success analysis of current treatments.
- Information about what we can do from the root to crown in the light of different clinical scenarios in primary and permanent teeth
- Working with NeoPUTTY and NeoSealer FLo materials on 3D models
Dr. Uğur Tokay was born in Aksaray in 1986. He completed his primary, secondary and high school education in Aksaray. He qualified from the Faculty of Dentistry of Süleyman Demirel University in 2010, and in the same year, he started his PhD education at Ondokuz Mayıs University, Faculty of Dentistry, Department of Paediatric Dentistry. He completed his PhD in 2014.
Between the years of 2014 and 2019, he worked as a consultant specialist in different private clinics. He has been working at the Private Premiumdent Oral and Dental Health Polyclinic since September 2019.
Dr. Uğur Tokay is a member of CAD Academy, CEREC Doctors, International Association of Paediatric Dentistry and European Academy of Paediatric Dentistry. He also gives trainings as a CE Certified trainer of Dentsply Sirona.
Dr. Uğur Tokay's special interests are preventive, restorative and aesthetic treatments for children and adolescents, regenerative endodontics, traumatic dental injuries and digital pediatric dentistry.
LUCİANO ZAFFARANO DDS – MS
Specialist in Paediatric Dentistry. Adjunct Professor in Paediatric Dentistry at University of Perugia.
"Direct restorations in primary teeth: what’s new? "
In the last few decades, much progress has been made in regard to the restorative management of carious lesions. These include developments in early diagnosis, selective caries removal, modified atraumatic restorative techniques, new adhesive systems and restorative materials. We will discuss how these improvement can help the clinician in a routine treatment as direct restoration in primary teeth.
Degree in Dental medicine at University of Parma.
Master of science in Aesthetic restorative dentistry at University of Bologna.
Specialist in Paediatric dentistry at University of Milan.
Adjunct professor in Paediatric dentistry at University of Perugia.
Member of IAPD committee 2021-2023.
Reviewer for peer reviewed dental journal and lecturer in paediatric dentistry.
Member of Italian Society of Paediatric Dentistry, Italian Society of Special needs Dentistry, Italian Academy of Conservative and Restorative Dentistry, European Academy of Paediatric Dentistry and International Association of Pediatric Dentistry.
"Early interceptive treatment of malocclusions with LM-Activator Eruption guidance appliance"
Early orthodontic treatment – Eruption Guide Appliances – LM Activators
The proposed training course aims to propose a therapeutic diagnostic vision of early orthodontic treatment (EOT) using the guidance of the eruption process of the dental elements.
Starting with a reminder of the growth mechanisms that can be exploited in the EOT we will move on to an examination of the malocclusions that can be treated early and their methods of treatment using the various preformed devices available on the market. Indications, therapeutic strategies and related timing will be examined.
The whole course is based on the analysis of clinical cases in the light of the scientific evidence published in the sector.
In the practical part the clinical use of these devices will be approached (how to choose the right model, when and how to modify them, when to change the type of appliance) using LM Activator with typodonts and dental casts
It will be possible to carry out moments of comparison on cases brought by the participants to the course.
Time will be left for questions and solving practical problems.
(DDS. Orth. Spec.)
Degree in Dentistry. (1985) - Master "Ricketts bioprogressive technique 1 ° level" (1987) - and 2 ° level (1988) Specialization in orthodontics University of Naples (1990-93) Annual specialization course in "Interceptive Orthodontics" University of Pavia ( 1995) Master in "Diagnosis and therapy of temporomandibular joint problems" University of Chieti (1996) - Master in "Cranio-Facial Pain" University of Chieti (1998) - Master in Cranio-mandibular Disorders University of Naples (2003-04) Master in "Clinical Risk Management" University of Sannio (2010-2011) Founding member of the Italian Society of Interceptive Orthodontics in 2004. Ordinary member of the Italian Society of Orthodontics (S.I.D.O.) Since 2003 he has been a member of the Italian Board of Orthodontics (IBO). 2006 he is member of the European Board of Orthodontics (EBO). From 2002 to 2007 and from 2012 to 2014 he teaches as an adjunct professor in "Interceptive Orthodontics and Functional Therapy" and from the academic year 2007 to 2011 he teaches in "technique with straight arch" at the School of Specialization in Orthodontics of the 'University of Naples Federico II. From 2017 to 2019 he teaches "Interceptive Orthodontics" at the School of Specialization in Pedodontics of the University of Naples. He carries out his clinical activity privately in Caserta and works in the ASL CE as an outpatient specialist in Interceptive Orthodontics.
Skills and Expertise